NursingNotes
  • login
  • signup
  • Latest News
  • Clinical Updates
  • Professional
  • Education
  • Opinion
No Result
View All Result
NursingNotes
No Result
View All Result

Home > News > Research

Hydroxychloroquine trials halted amid safety fears

Patients and healthcare professionals are encouraged to report suspected side effects from hydroxychloroquine via the Yellow Card COVID-19 reporting site.


17 June 2020
Hydroxychloroquine AC384

Shutterstock

There are emerging concerns about the use of hydroxychloroquine in COVID-19 patients.

The Medicines and Healthcare products Regulatory Agency (MHRA) has instructed UK clinical trials using hydroxychloroquine to treat or prevent COVID-19 to suspend the recruitment of further participants.



No new participants will be recruited to these trials until further data which justifies their continuation have been provided, and additional safety measures have been implemented.

This comes from advice from the Commission on Human Medicines, which met on 1 and 5 June 2020, after they reviewed the data that had been sent for each trial in response to MHRA requests.

This follows the emerging concerns about the use of hydroxychloroquine in COVID-19 and took into consideration the results from two different trials.

This includes the UK’s RECOVERY (Randomised Evaluation of COVid-19 thERapY) trial which has provided convincing evidence of no meaningful mortality benefit in hospitalised patients with COVID-19.


Report any suspected side effects.

Published only yesterday, preliminary results show Dexamethasone, an inexpensive steroid, can reduce the mortality rate of the COVID-19 presenting with severe respiratory complications.

Hydroxychloroquine and chloroquine are licensed in the UK to treat different health conditions such as malaria, rheumatoid arthritis, and lupus.

Dr. June Raine, MHRA’s CEO, said: “Neither hydroxychloroquine nor chloroquine are licensed to treat COVID-19 related symptoms or to prevent infection. It is important to note that patients taking hydroxychloroquine and chloroquine to treat other health conditions can continue to do so, as advised by their healthcare professional, as the balance of benefits and risks remains favourable in the licensed uses.”

The Yellow Card scheme is MHRA’s system of monitoring the safety of medicines and medical devices in the UK and it acts as an early warning system to identify new and strengthen existing safety information.


Patients or healthcare professionals can report any suspected side effects from hydroxychloroquine or chloroquine taken by patients with COVID-19 via the Yellow Card COVID-19 reporting site: coronavirus-yellowcard.mhra.gov.uk



Popular

Patient face mask in GP

GP practices can now deregister patients for ‘unrealistic service demands’

2 June 2022

student nurse staff nurse

Student nurses ‘used and abused’ on placements

13 June 2022

RCN

Nursing staff demand immediate review of ‘not fit for purpose’ Agenda for Change pay and conditions

8 June 2022

Insight

Busy A&E waiting room

‘The NHS is having its worst winter ever – and the reasons run much deeper than COVID’

28 January 2022

Hospital curtain intensive care

‘During the Downing Street Christmas Party we were caring for dying patients and forbidden from seeing family’

8 December 2021

Vaccine inPPE

‘Making vaccination compulsory for NHS frontline workers likely to make patients suffer’

19 November 2021


Related Posts

Close-up the positive young nurse who is dialing medicine into the syringe indoors
Clinical

Hospitals reintroduce compulsory mask wearing for staff and patients

29 June 2022
London, England, UK, January 22nd 2022, Long covid symptoms sign on pharmacy shop window UK
Clinical

Tribunal rules long-Covid is a disability

21 June 2022
Nurse putting PPE in bin
News

Nurses may not have died if the Government purchased ‘decent’ PPE

15 June 2022
NursingNotes

© 2019 NursingNotes.co.uk

Navigate Site

  • Who are we?
  • Terms of Service
  • Privacy Policy
  • Contact Us
  • Agenda for Change Pay Scales

Follow Us

No Result
View All Result
  • Latest News
  • Clinical
  • Education
  • Health Politics
  • Opinion
  • Resources

© 2019 NursingNotes.co.uk